The 2026 US Open women's doubles tournament saw a major shake-up, as defending champions Gabriela Dabrowski and Erin Routliffe chose not to compete together, instead pairing with new partners—Dabrowski with Luisa Stefani and Routliffe with Aldila Sutjiadi. Both former champions were ultimately eliminated by the surging duo of Ashlyn Krueger and Robin Montgomery, who defeated Dabrowski in the semifinals and Routliffe in the quarterfinals. Meanwhile, Taylor Townsend and Kateřina Siniaková were chasing history, with Townsend aiming for a career Grand Slam and Siniaková seeking a second career Grand Slam in women's doubles, while other contenders Kristina Mladenovic and Hsieh Su-wei fell short in the first round and quarterfinals, respectively. The tournament's seedings were based on WTA rankings as of August 31, 2026, and the entry list featured a notable substitution: Elisabetta Cocciaretto and Yulia Putintseva were replaced by Ena Shibahara and Lanlana Tararudee. The draw followed a standard format, divided into top and bottom halves with four sections each, leading to the finals.