The 2025 USC Trojans football team, led by fourth-year head coach Lincoln Riley, competed as a second-year member of the Big Ten Conference during the 2025 NCAA Division I FBS season. Playing at the Los Angeles Memorial Coliseum, the Trojans drew an average home attendance of 67,783, ranking 22nd among all college football teams. Their demanding schedule featured rivalry clashes against Notre Dame, Oregon, and UCLA, and concluded with a bowl appearance against TCU in the Alamo Bowl. The roster saw significant turnover, losing 27 players via the transfer portal while adding 16 new transfers. A notable group of players, including running back Woody Marks and offensive lineman Jonah Monheim, declared for the 2025 NFL Draft, underscoring the program's continued talent development.