The 2025 season was a historic one for Inter Miami CF, as the club secured its first-ever MLS Cup title by defeating the Vancouver Whitecaps 3–1 at Chase Stadium. The campaign began with major changes, including Javier Mascherano taking over as head coach from the departed Tata Martino in November, while star striker Luis Suárez signed a one-year extension to stay with the team. As the defending record-holding Supporters' Shield champions, Miami competed in the CONCACAF Champions Cup, where a notable match in Kansas City was played in extreme sub-zero temperatures, with Lionel Messi scoring the only goal. The team also made history by participating in their first FIFA Club World Cup, hosting the tournament's opening match on June 15 at Hard Rock Stadium. This season marked the club's final year at Chase Stadium in Fort Lauderdale, with a move to the new Nu Stadium planned for 2026. The regular season opened with a dramatic 2–2 draw against New York City FC, featuring a stoppage-time equalizer by Telasco Segovia after Miami played most of the game with ten men.