Yūsuke (or Yusuke/Yuusuke) is a prevalent masculine Japanese given name, distinguished by its numerous kanji spellings. These diverse combinations often convey positive meanings like "courage," "masculinity," or "friend," frequently paired with characters signifying "to help" or "mediate." Beyond kanji, the name can also be written in hiragana (ゆうすけ) or katakana (ユウスケ).

Many accomplished individuals bear this name across a wide spectrum of professions. Historically, Yusuke Hagihara (1897–1979) was a renowned astronomer who significantly advanced celestial mechanics. In contemporary culture, the name is prominent among figures like acclaimed manga artist Yusuke Murata (born 1978), known for One-Punch Man, and rock singer Yusuke Chiba (born 1968) of Thee Michelle Gun Elephant fame. This extensive array of notable persons, spanning sports, entertainment, and academia, highlights the name's enduring popularity and versatility in Japanese society.