Spider-Girl is a mantle shared by several Marvel superheroines, most famously Mayday Parker, the daughter of Peter Parker and Mary Jane Watson, who debuted in the pages of What If and gained a surprisingly long-running solo series in the MC2 universe. In the mainstream Earth-616, Anya Corazon became the first Latina Spider-Girl in a short-lived 2010 series that was cancelled after just eight issues. A decade later, Gwen Warren—a mutant hybrid created by the Jackal using DNA from Gwen Stacy, the Spider-Queen, and Cyclops—took the name in 2023 as a member of the X-Men. The newest holder, Maka Akana, is a villainous protégé of Bullseye who adopted the title in 2024 to mock Spider-Boy and then kept it for herself. Beyond these, alternate versions like the clone April Parker (who later became "Mayhem") and the superhero group "The Spider-Girls" further expand the legacy, showing how the name evolves from hero to villain across the Marvel multiverse.